On 17 February 2008, Sara Cox presented her last show for six months before leaving for maternity leave to have her second child. Annie Mac presented the show during her absence. Sara Cox later covered for Jo Whiley who was on maternity leave between October 2008 and February 2009. Following Whiley’s return, Cox returned to weekends to present a Sunday mid-morning show, broadcasting between 10am and 1pm.
In March 2010 Sara Cox went on maternity leave for the third time, leaving her show in the hands of the newest Radio 1 presenter, Matt Edmondson. She returned to the airwaves on 9 August 2010 to cover for Fearne Cotton for three weeks. Sara Cox made a self-confessed unexpected return to the breakfast show on 2 September 2010, as she sat in for the poorly Chris Moyles.
In August 2012, it was announced that Sara Cox would cover Fearne Cotton’s show on BBC Radio 1 weekdays from 10:00 – 12:45 whilst Cotton is on maternity leave. Sara Cox presented Radio 1’s mid-morning programme while Fearne Cotton went on maternity leave. She was replaced by Matt Edmondson on Sunday mornings. After Cotton’s return, Sara Cox did various cover shows; her final show for Radio 1 was on Monday 17 February 2014.
In June 2011, Sara Cox began hosting the fourth series of the comedy programme Hot Gossip on BBC Radio 2, covering for Claudia Winkleman, who chose not to present the series as she was heavily pregnant at the time. During the first week of March 2012, Sara Cox covered for Alex Lester on BBC Radio 2. She has also covered for Janice Long on the same station.
In the last week of September 2012, Sara Cox covered for Vanessa Feltz on BBC Radio 2 in the 5:00 to 6:30 slot; during this week, she was immediately followed by Zoe Ball, who was filling in for Chris Evans on the breakfast show. Sara Cox joined BBC Radio 2 for her first regular show each Saturday night from 10 pm to midnight, presenting an 80s show to complement the weekend 60s and 70s decade shows. The show began on Saturday 5 October 2013.
Sara Cox has presented shows for Steve Wright, Ken Bruce and Simon Mayo when they have been away from the station. Starting 7 July 2014, Sara Cox presented The Chris Evans Breakfast Show while Evans was off for a week. She also presented The Chris Evans Breakfast Show again, while the original members were on holiday for a week from 29 September 2014. Sara Cox has now been made the main and first choice cover presenter for the breakfast show.
In July 2007, Sara Cox presented The Album Chart Show on Channel 4, and appeared as a guest star on the Sky1 show Angela and Friends in November 2009 and as Guest Presenter in January 2010. Also in 2010, she appeared as a team captain on What Do Kids Know? along with Rufus Hound and Joe Swash on the Watch channel.
Sara Cox commentated for the semi-finals of the Eurovision Song Contest on BBC Three with fellow BBC Radio DJ Scott Mills from the 2011 Contest through till the 2012 Contest. Sara Cox was replaced by Ana Matronic starting from the 2013 Contest.
On 21 October 2014, Sara Cox guest presented a Children in Need episode of The Great British Sewing Bee. In 2015, she appeared as a panellist on an episode of Through the Keyhole on ITV. In April 2015, it was announced that Sara Cox would present The Great Pottery Throw Down for BBC Two. The first series began in November 2015. Since February 2016, Cox has co-presented Too Much TV, a daily magazine show on BBC Two.